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Hypercholesterolemia and the regulation of adrenal steroidogenesis in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats

โœ Scribed by Michael J. DiBartolomeis; Robert W. Moore; Richard E. Peterson; Colin R. Jefcoate


Book ID
113206798
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
982 KB
Volume
85
Category
Article
ISSN
0041-008X

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Plasma concentrations of pituitary hormo
โœ Moore, Robert W. ;Parsons, Jonathan A. ;Bookstaff, Robert C. ;Peterson, Richard ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 835 KB

Experiments were conducted to test the hypothesis that acute TCDD toxicity is associated with pituitary hypofunction. Sexually mature male Sprague-Dawley rats were given graded doses of TCDD (0-100 pglkg) and evaluated 7 days later. Despite pronounced hypophagia and body weight loss, plasma concentr