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Hyperbaric effects on sensorimotor reactivity studied with acoustic startle in the rat

✍ Scribed by Jean-Marc David; Jean-Jacques Risso; Michel Weiss; François Brue; Jean Pellet


Book ID
118353446
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
918 KB
Volume
42
Category
Article
ISSN
0031-9384

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Cocaine (2.5-10 mg/kg) caused a dose-related increase in the amplitude of the acoustic startle reflex in rats. In contrast, procaine (5 40 mg/kg) caused a dose-related decrease in startle, indicating that the effects of cocaine could not be ascribed to its local anesthetic effects. Cocaine's excitat