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Hyperactivation of mTOR critically regulates abnormal osteoclastogenesis in neurofibromatosis Type 1

✍ Scribed by Xijie Yu; Junrong Ma; Janet Hock


Book ID
116323731
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
39 KB
Volume
47
Category
Article
ISSN
8756-3282

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Hyperactivation of mTOR critically regul
✍ Junrong Ma; Mi Li; Janet Hock; Xijie Yu πŸ“‚ Article πŸ“… 2011 πŸ› Elsevier Science 🌐 English βš– 916 KB

## Abstract Individuals with nerofibromatosis Type 1 (NF1) frequently suffer a spectrum of bone pathologies, such as abnormal skeletal development (scoliosis, congenital bowing, and congenital pseudoarthroses, etc), lower bone mineral density with increased fracture risk. These skeletal problems ma