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Hydroxyurea: Induction of breaks in template strands of replicating DNA

✍ Scribed by Ian G. Walker; R.W. Yatscoff; R. Sridhar

Book ID
119406539
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
288 KB
Volume
77
Category
Article
ISSN
0006-291X

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## Abstract Two mechanisms are available for the repair of DNA double‐strand breaks (DSBs) in eukaryotic cells: homology directed repair (HDR) and non‐homologous end‐joining (NHEJ). While NHEJ is not restricted to a particular phase of the cell cycle, it is incapable of accurately repairing DBSs th