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Hydroxyurea enhances SMN2 gene expression through nitric oxide release

✍ Scribed by Cheng Xu; Xin Chen; Susanna M. Grzeschik; Madhuri Ganta; Ching H. Wang

Publisher
Springer
Year
2010
Tongue
English
Weight
255 KB
Volume
12
Category
Article
ISSN
1364-6745

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## Abstract Nitric oxide (NO) can regulate osteoblast activity. In this study, we evaluated the effects of pretreatment with a low concentration of NO on osteoblast injuries induced by a high level of NO and its possible molecular mechanisms. Exposure of osteoblasts to 0.3 mM sodium nitroprusside (