Twenty-three children with destructive polyarticular juvenile rheumatoid arthritis (JRA) were treated for 0 . 5 4 3 years (median 1.6 years) with weekly doses of methotrexate (MTX) (0.11-0.6 mg/kg/week). Serum levels of MTX at 1 hour and at 24 hours after drug administration were obtained at each do
Hydroxychloroquine does not decrease serum methotrexate concentrations in children with juvenile idiopathic arthritis
✍ Scribed by Jarkko Haapasaari; Hannu Kautiainen; Heikki Isomäki; Markku Hakala
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 232 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective To compare the safety and efficacy of parenteral methotrexate (MTX) at an intermediate dosage (15 mg/m^2^/week) versus a higher dosage (30 mg/m^2^/week) in patients with polyarticular‐course juvenile idiopathic arthritis (JIA) who failed to improve while receiving standard
## Abstract ## Objective To determine the prevalence of temporomandibular joint (TMJ) disease in a cohort of children with new‐onset juvenile idiopathic arthritis (JIA), and to compare magnetic resonance imaging (MRI) with ultrasound (US) for the detection of acute and chronic changes of TMJ arthr