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Hydroxamide derivatives of short-chain fatty acids are potent inducers of human fetal globin gene expression

✍ Scribed by Evangelia Skarpidi; Hua Cao; Birgit Heltweg; Brian F White; Ronald L Marhenke; Manfred Jung; George Stamatoyannopoulos

Book ID: 114216968
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 167 KB
Volume: 31
Category: Article
ISSN: 0301-472X
DOI: 10.1016/s0301-472x(02)01030-5

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## Abstract It has been suggested that the short‐chain fatty acids (SCFAs) produced by anaerobic bacterial intestinal fermentation of soluble fiber may regulate lipid metabolism in intestine, thus reducing plasma cholesterol levels. However, the exact mechanism of action of SCFAs in lowering choles