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Hydroxamic acids II: Kinetics and mechanisms of hydroxyaminolysis of succinimide

✍ Scribed by Robert E. Notari


Publisher
John Wiley and Sons
Year
1969
Tongue
English
Weight
572 KB
Volume
58
Category
Article
ISSN
0022-3549

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✦ Synopsis


Factors affecting the stability of the hydroxamic acid-iron complex have been studied. It has been shown that the iron concentration is the most important factor for complex stability.

Conditions for a stable complex have been developed and found to be superior to those utilizing HzOz.

An assay for succinimide has been designed and found to be reproducible on consecutive days.

The hydroxyaminolysis reaction has been successfully carried out in an aqueous medium. Therefore the assay is potentially useful for pharmaceutical systems.


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