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Hydrophobic Mismatch and the Incorporation of Peptides into Lipid Bilayers: A Possible Mechanism for Retention in the Golgi †

✍ Scribed by Webb, Richard J.; East, J. Malcolm; Sharma, Ram P.; Lee, Anthony G.


Book ID
127087751
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
115 KB
Volume
37
Category
Article
ISSN
0006-2960

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Liposomes consisting of egg yolk phosphatidylcholine and hydrophobic peptides Nps-and C1--+H,-(Met-Met-Leu),-OEt ( n = 6-10) with various polypeptide chain lengths were prepared by the sonication method. The conformation of the peptides incorporated into the liposomes was examined by CD spectroscopy