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Hydrolytic degradation and protein release studies of thermogelling polyurethane copolymers consisting of poly[(R)-3-hydroxybutyrate], poly(ethylene glycol), and poly(propylene glycol)

โœ Scribed by Xian Jun Loh; Suat Hong Goh; Jun Li

Book ID
103825450
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
655 KB
Volume
28
Category
Article
ISSN
0142-9612

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Biodegradable PHB-PEG multi-block polyurethane copolymers comprising PHB blocks (M n : 1100, 1740 and 3240) and PEG blocks (M n : 1960, 3250, 4150 or 7950) were synthesized followed by characterization by GPC, 1 H NMR, and FT-IR. The PHB contents ranged from 9 to 62% by weight. The copolymers displa