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Hydrolysis of a series of parabens by skin microsomes and cytosol from human and minipigs and in whole skin in short-term culture

✍ Scribed by Christopher Jewell; Jeffery J. Prusakiewicz; Chrisita Ackermann; N. Ann Payne; Gwendolyn Fate; Richard Voorman; Faith M. Williams


Book ID
113924192
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
549 KB
Volume
225
Category
Article
ISSN
0041-008X

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Adult and foetal human skin samples maintained in short-term organ culture were treated topically with solutions of coal-tar, creosote or bitumen, then DNA was isolated and analysed by 32P-post-labelling for the presence of aromatic DNA adducts. Autoradiographs of the 32P-labelled adducts resolved o