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Hydrolysis and protection from hydrolysis of enkephalins in human plasma

✍ Scribed by Mario Marini; Gianna Roscetti; Lucilla Bongiorno; Alessandra Urbani; L. Giorgio Roda


Publisher
Springer
Year
1990
Tongue
English
Weight
599 KB
Volume
15
Category
Article
ISSN
0364-3190

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In humans, the plasma enzyme butyrylcholinesterase, BChE (EC 3.1.1.8), mediates the in vivo plasma hydrolysis of cocaine to the pharmacologically inactive metabolite ecgonine methyl ester, EME. This enzyme has been purified from human plasma to investigate the potential as a treatment for cocaine in