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Hydrolysis and Oxidation of 1H-Benzotriazole-carboxylic Acid Esters by Rat Liver Microsomes

✍ Scribed by Sylvia Jacobi; Hermann Hoffmann


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
296 KB
Volume
323
Category
Article
ISSN
0365-6233

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We studied the in vitro hydrolysis of acetylsalicylic acid (ASA) to salicylic acid (SA) catalysed by microsomal preparations from liver, kidney, small intestine and stomach mucosas and blood serum of adult female and male rats. Hepatic microsomes from male rats had the highest specific activity: 42.