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Hydrolysis and binding of a toxic stereoisomer of soman in plasma and tissue homogenates from rat, guinea pig and marmoset, and in human plasma

โœ Scribed by Leo P.A. De Jong; Corry van Dijk; David Berhitoe; Hendrik P. Benschop


Book ID
115783206
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
735 KB
Volume
46
Category
Article
ISSN
0006-2952

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The plasma protein binding of celecoxib was determined for animals and humans using in vitro and ex vivo methods. Eight, healthy, human volunteers (three male, five female, 20-39 years) received celecoxib (600 mg) BID for 7 days, blood samples were collected and concentrations of bound and unbound c