Hydrogen/fluorine retuning tomography. applications to 1h image-guided volume-selective 19f spectroscopy and relaxometry of perfluorocarbon emulsions in tissue
✍ Scribed by G. Schnur; R. Kimmich; R. Lietzenmayer
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 620 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0740-3194
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✦ Synopsis
A hardware modification which permits the record of I9F images, spectra, and relaxation times with a 'H tomography bird-cage resonator is described. Changing the spectrometer frequency from 'H to "F resonance and vice versa is possible without removing the object to be investigated. This hydrogen/fluorine retuning tomography (HYFY) technique permits studies of identical slices or volume elements with 'H as well as with I9F resonance. In particular, it is possible to localize volume elements on the basis of multislice proton images and then to investigate these volume elements with fluorine magnetic resonance by the aid of volume selection methods. For this purpose, pulse sequences for the localized and spectroscopically resolved determination of spin-lattice and transverse relaxation times have been developed. The applicability of the techniques has been demonstrated by the aid of phantom samples as well as with excised porcine organs which have been perfused with perfluorocarbon emulsions. o 1990 Academic press, Inc.