𝔖 Bobbio Scriptorium
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Hydrogen peroxide inhibits mTOR signaling by activation of AMPKα leading to apoptosis of neuronal cells

✍ Scribed by Chen, Long; Xu, Baoshan; Liu, Lei; Luo, Yan; Yin, Jun; Zhou, Hongyu; Chen, Wenxing; Shen, Tao; Han, Xiuzhen; Huang, Shile


Book ID
109885520
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
653 KB
Volume
90
Category
Article
ISSN
0023-6837

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## Abstract Oleanolic acid (OA), a pentacyclic triterpenoid exhibits potent anti‐tumor activity against many tumor cell lines. But the mechanisms through which OA inhibits osteosarcoma cells are not known. The mammalian target of rapamycin (mTOR) serves as a central regulator of cell growth, prolif