## Abstract Oligodendrocytes, the myelinβforming cells of the CNS, are specifically sensitive to oxidative stress and respond by the onset of programmed cell death (PCD). To further unravel the molecular events underlying their enhanced susceptibility, we have investigated whether mitochondrial dam
β¦ LIBER β¦
Hydrogen peroxide-induced necrotic cell death in cardiomyocytes is independent of matrix metalloproteinase-2
β Scribed by Ali, Mohammad A.M.; Kandasamy, Arulmozhi D.; Fan, Xiaohu; Schulz, Richard
- Book ID
- 120975335
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 1004 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0887-2333
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## Abstract Intracellular events following paclitaxel binding to microtubules that lead to cell death remain poorly understood. Because reactive oxygen species (ROS) are involved in the cytotoxicity of anticancer agents acting through independent molecular targets, we explored the role of ROS in pa