Hydrogen Peroxide-induced Cell Death in Arabidopsis: Transcriptional and Mutant Analysis Reveals a Role of an Oxoglutarate-dependent Dioxygenase Gene in the Cell Death Process

Analysis of the role of Hsp25 phosphoryl

Analysis of the role of Hsp25 phosphorylation reveals the importance of the oligomerization state of this small heat shock protein in its protective function against TNFα- and hydrogen peroxide-induced cell death

✍ Xavier Préville; Heidi Schultz; Ursula Knauf; Matthias Gaestel; André-Patrick Ar 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 367 KB 👁 2 views

The role of murine Hsp25 phosphorylation in the protection mediated by this protein against TNF␣-or H 2 O 2 -mediated cytotoxicity was investigated in L929 cell lines expressing wild type (wt-) or nonphosphorylatable (mt-) Hsp25. We show that mt-Hsp25, in which the phosphorylation sites, serines 15