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Hydrogen peroxide and redox modulation sensitize primary mouse hepatocytes to TNF-induced apoptosis

✍ Scribed by Derick Han; Naoko Hanawa; Behnam Saberi; Neil Kaplowitz


Book ID
113630007
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
818 KB
Volume
41
Category
Article
ISSN
0891-5849

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πŸ“œ SIMILAR VOLUMES


Topoisomerase inhibitor camptothecin sen
✍ Hannes Hentze; Markus Latta; Gerald KΓΌnstle; Saravanakumar Dhakshinamoorthy; Poh πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 460 KB

Topoisomerases are nuclear enzymes that maintain and modulate DNA structure. Inhibitors of topoisomerases like camptothecin (CPT), etoposide, and others are widely used antitumor drugs that interfere with transcription, induce DNA strand breaks, and trigger apoptosis preferentially in dividing cells