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Hydrogen bonds involving sulfur atoms in proteins

✍ Scribed by Lydia M. Gregoret; Stephen D. Rader; Robert J. Fletterick; Fred E. Cohen


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
694 KB
Volume
9
Category
Article
ISSN
0887-3585

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✦ Synopsis


Intrachain hydrogen bonds are a hallmark of globular proteins. Traditionally, these involve oxygen and nitrogen atoms. The electronic structure of sulfur is compatible with hydrogen bond formation as well. We surveyed a set of 85 high-resolution protein structures in order to evaluate the prevalence and geometry of sulfur-containing hydrogen bonds. This information should be of interest to experimentalists and theoreticians interested in protein structure and protein engineering.


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