Hydrogen bonding motif in 2-hydroxy-1,4-naphthoquinone
β Scribed by N. R. Dhumal; A. V. Todkary; S. Y. Rane; S. P. Gejji
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 329 KB
- Volume
- 113
- Category
- Article
- ISSN
- 1432-2234
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π SIMILAR VOLUMES
The rational design of a system which mimics the molecular recognition properties of carboxylic acids but displays markedly different reactivity is presented. 10-Hydroxy-10,9-borazaro phenanthrene is predicted by both structural analogy with carboxylic acids and ab initio calculations to form cyclic
Oxidation of four l -(25dimethoxyaryl)pyrrolidin-2-oneswith silver(H) oxide in acidic medium gave the corresponding quinones in moderate to good yield. 1.4.Naphthoquinone and L-methoxy-A'-pyrroline reacted in methanol to give 2-(3-methoxycarbonylpropylamino)-l.4-naphthoquinone
The short-term toxicity of 2-hydroxy-1,4-naphthoquinone (lawsone) and 2-methyl-1,4-naphthoquinone (menadione) has been compared in rats. 2-Methyl-I ,4-naphthoquinone has been shown previously to cause haemolytic anaemia in animals, and this was confirmed in the present experiment. 2-Hydroxy-l,4-nap
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The mechanisms of toxicity to isolated rat hepatocytes of two structurally related naphthoquinones have been studied. Both 5-OH-1,4-naphthoquinone (5-OH-1,4-NQ; juglone) and 2-OH-1,4-naphthoquinone (2-OH-1,4-NQ; lawsone) caused a concentration-dependent cytotoxicity to hepatocytes which was preceded