Hydrogen Bonding-Induced Transformation of Network Aggregates into Vesicles - A Potential Method for the Preparation of Composite Vesicles

✍ Scribed by Jian Xiang Zhang; Xiao Dong Li; Mei Qiu Yan; Li Yan Qiu; Yi Jin; Kang Jie Zhu

• Book ID: 102494481
• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 493 KB
• Volume: 28
• Category: Article
• ISSN: 1022-1336
• DOI: 10.1002/marc.200600814

✦ Synopsis

Abstract

While network‐like assemblies are formed by amphiphilic polyphosphazenes with poly(N‐isopropylacrylamide) and ethyl tryptophan as side groups in aqueous solution, a significant morphology transformation is observed when small molecules that exhibit hydrogen‐bonding interactions with amphiphilic copolymers are introduced during the preparation of polymeric assemblies through a dialysis procedure. Depending on copolymer composition and the content of small molecules introduced, aggregates ranging from general vesicles, high‐genus vesicles, to well‐defined nanospheres can be prepared successfully as clearly evidenced by TEM observation, which suggests this procedure should be a novel approach to prepare composite vesicles.

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