Hydrogen Bond Vibrations of 2-Aminopyridine·2-Pyridone, a Watson−Crick Analogue of Adenine·Uracil
✍ Scribed by Müller, Andreas; Talbot, Francis; Leutwyler, Samuel
- Book ID
- 120282139
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 211 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0002-7863
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📜 SIMILAR VOLUMES
The formation energies of 2-aminopyridine dimer and 2-aminopyridine-2-pyridone complex were measured in C,D, solution by 'H-NMR spectroscopy and values of 25.1 and 44.6 kJ/mol were obtained. The former value is about twice the magnitude of hydrogen bond energies which are generally observed for the
## Abstract 2‐Pyridone (pyridin‐2‐one) is a mimic of the uracil and thymine nucleobases, with only one NH and CO group. It provides a single H‐bonding site, compared to three for the canonical pyrimidine nucleobases. Employing the supersonically cooled 9‐methyladenine⋅2‐pyridone (9MAd⋅2PY) comple