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Hydrogels: from controlled release to pH-responsive drug delivery

✍ Scribed by Piyush Gupta; Kavita Vermani; Sanjay Garg


Book ID
114383952
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
342 KB
Volume
7
Category
Article
ISSN
1359-6446

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pH-sensitive hydrogels based on methacrylic acid (MAA) and poly(ethylene glycol) macromonomer (PEGMEMA) entrapping diltiazem hydrochloride (DILÁHCl) were synthesized inside soft gelatin capsules for use as a new dosage form for oral drug administration. Different monomer compositions were used to ev