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Hydrocortisone Suspension and Hydrocortisone Tablets Are Not Bioequivalent in the Treatment of Children with Congenital Adrenal Hyperplasia

โœ Scribed by Merke, D. P.


Book ID
120559797
Publisher
Endocrine Society
Year
2001
Tongue
English
Weight
313 KB
Volume
86
Category
Article
ISSN
0021-972X

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The conventional treatment of CAH with hydrocortisone (16-19 mg/m2 per day) and 9 alpha-F-cortisol (just enough to normalise renin concentrations, started at 07:00 h) was ineffective in suppressing the early morning rise of 17-OH-progesterone and in turn androgens in about 20% of our patients. The p