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Hydrocarbon solvents: effect on calcium mediated events in liposomes

โœ Scribed by Jean Rabovsky; Karl J. Marion; Harold Resnick

Book ID
103038779
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
473 KB
Volume
37
Category
Article
ISSN
0009-3084

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โœฆ Synopsis

The effect of hydrocarbon solvents on membranes was investigated by measuring the inhibition of Ca2รท-induced turbidity in liposomes. Chloroform, carbontetrachloride, 1,1,1trichloroethane, hexane, cyclohexane and benzene protected against Ca~'-induced turbidity, and the concentration of each solvent required for a 50% decrease was in the millimolar range. Double-reciprocal plot analysis was consistent with the presence of solvent binding sites on the membrane.

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