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Hybridization of mRNA and pre-mRNA with the sequences forming double-stranded structures in pre-mRNA

✍ Scribed by A. P. Ryskov; S. A. Limborska; G. P. Georgiev

Publisher
Springer
Year
1973
Tongue
English
Weight
225 KB
Volume
1
Category
Article
ISSN
0301-4851

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✦ Synopsis

About 25~o of the double-stranded sequences isolated from pre-mRNA are able to hybridize, after melting, with either mRNA or non-melted pre-mRNA. The retention of one branch of pre-mRNA hairpin in mRNA was suggested. It was also found that in addition to the hairpin-like structures comprising about 3~ of the total sequences another 15~ of the pre-mRNA sequences can form double-stranded structures upon annealing over a broad interval of Cot values.

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