Hyaluronic acid produced by human synovial fibroblasts. Effect of polyinosinic-polycytidylic acid (POLY I:C) and interferon

Interrelationship between stimulation of

Interrelationship between stimulation of prostaglandin e and hyaluronate production by poly (i).Poly (c) and interferon in synovial fibroblast culture

✍ Michael Yaron; Ilana Yaron; Chana Wiletzki; Uriel Zor 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 English ⚖ 351 KB 👁 1 views

## Abstract The interferon‐inducer, polyinosinate. Polycyctidylate [Poly (I). Poly (C)] stimulated both prostaglandin E (PGE) and hyaluronic acid (HA) production by human cultured synovial fibroblasts. Increased accumulation of PGE in the medium was noted within 3 hours of culture, while accumulati