Dickkopf1: A tumor suppressor or metasta
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Mitchell E. Menezes; Daniel J. Devine; Lalita A. Shevde; Rajeev S. Samant
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Article
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2011
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John Wiley and Sons
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French
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## Abstract Dickkopf1 (DKK1), a secreted inhibitor of the Wnt/Ξ²βcatenin pathway, is a negative regulator of bone formation. DKK1 acts as a switch that transitions prostate cancer bone metastases from osteolytic to osteoblastic and also is an active indicator of poor outcome for multiple myeloma. Ho