Hutterite brothers both affected with two forms of limb girdle muscular dystrophy: LGMD2H and LGMD2I

The most common mutation in FKRP causing

The most common mutation in FKRP causing limb girdle muscular dystrophy type 2I (LGMD2I) may have occurred only once and is present in Hutterites and other populations

✍ Patrick Frosk; Cheryl R. Greenberg; Alysa A.P. Tennese; Ryan Lamont; Edward Nyle 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 223 KB

## Communicated by Jacques Beckmann Limb girdle muscular dystrophy (LGMD) is common in the Hutterite population of North America. We previously identified a mutation in the TRIM32 gene in chromosome region 9q32, causing LGMD2H in approximately two-thirds of the 60 Hutterite LGMD patients studied t