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Huperzine A, but not tacrine, stimulates S100B secretion in astrocyte cultures

✍ Scribed by Lunardi, Paula; Nardin, Patrícia; Guerra, Maria Cristina; Abib, Renata; Leite, Marina Concli; Gonçalves, Carlos-Alberto

Book ID
123578497
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
687 KB
Volume
92
Category
Article
ISSN
0024-3205

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## Abstract Astrocytes sense, integrate, and respond to stimuli generated by neurons or neural injury; this response involves gap junction (GJ) communication. Neuronal vulnerability to injury increased when cocultures of astrocytes and neurons were exposed to GJ inhibitors. However, GJ uncoupling c