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Huntington's disease: new aspects on phenotype and genotype

✍ Scribed by Huifang Shang; Adrian Danek; Bernhard Landwehrmeyer; Jean-Marc Burgunder


Book ID
117754405
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
106 KB
Volume
18
Category
Article
ISSN
1353-8020

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Molecular aspects of Huntington's diseas
✍ Hobart W. Walling; Joseph J. Baldassare; Thomas C. Westfall πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 74 KB

Huntington's disease (HD) is a progressive neurodegenerative disease striking principally medium spiny GABAergic neurons of the caudate nucleus of the basal ganglia. It affects about one in 10,000 individuals and is transmitted in an autosomal dominant fashion. The molecular basis of the disease is