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Huntington's disease CAG trinucleotide repeats in pathologically confirmed post-mortem brains

✍ Scribed by Francesca Persichetti; Jayalakshmi Srinidhi; Lisa Kanaley; Pei Ge; Richard H. Myers; Kenneth D'Arrigo; Glenn T. Barnes; Marcy E. MacDonald; Jean-Paul Vonsattel; James F. Gusella; Edward D. Bird


Book ID
115641342
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
223 KB
Volume
1
Category
Article
ISSN
0969-9961

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Trinucleotide (CAG) repeat expansion in
✍ J. Benitez; E. Fernandez; P. Garcia Ruiz; M. Robledo; C. Ramos; J. Yebenes πŸ“‚ Article πŸ“… 1994 πŸ› Springer 🌐 English βš– 182 KB

Huntington's disease (HD) is a neurodegenerative and hereditary disease characterized by progressive movement disorders and mental and behavioral abnormalities. The HD gene is an expanding and unstable trinucleotide repeat (CAG repeat sequences). We studied 77 individuals from 38 families with HD in