Huntingtin Immunoreactivity in the Rat Neostriatum: Differential Accumulation in Projection and Interneurons
β Scribed by Christoph M. Kosinski; Jang-Ho Cha; Anne B. Young; Francesca Persichetti; Marcy MacDonald; James F. Gusella; John B. Penney Jr.; David G. Standaert
- Book ID
- 115606508
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 531 KB
- Volume
- 144
- Category
- Article
- ISSN
- 0014-4886
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We study the neurogenesis of a distinct subclass of rat striatum β₯-aminobutyric acid (GABA)ergic interneurons marked by the calcium-binding protein parvalbumin (PV). Timed pregnant rats are given an intraperitoneal injection of bromodeoxyuridine (BrdU), a marker of cell proliferation, on designated
On the basis of cytochemical and morphologic differences, two classes of gamma-aminobutyric acidergic (GABAergic) interneurons expressing calcium-binding proteins have been identified in the striatum of adult animals: neurons expressing either parvalbumin (PV) or calretinin (CR). The function of the