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Hunter syndrome: Gene deletions and rearrangements

✍ Scribed by Roseline Froissart; Jean-Luc Blond; Irene Maire; Pierre Guibaud; John J. Hopwood; Monique Mathieu; Dominique Bozon

Book ID
102260049
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
256 KB
Volume
2
Category
Article
ISSN
1059-7794

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Through cloning and deletion experiments on ColEl hybrids the rpoB gene (Rifr) was located on a physical restriction map; RNA polymerase binding studies showed no binding site within the structural gene. The genetic data and RNA polymerase binding studies lead to the conclusion that rp/L and rpoB ar