Humoral immune response to HTLV-1 basic leucine zipper factor (HBZ) in HTLV-1-infected individuals
✍ Scribed by Yoshimi Enose-Akahata, Anna Abrams, Raya Massoud, Izabela Bialuk…
- Book ID
- 120690876
- Publisher
- BioMed Central
- Year
- 2013
- Tongue
- English
- Weight
- 331 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1742-4690
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## Abstract HTLV‐1 infection causes adult T‐cell leukemia (ATL). The development of ATL is thought to be associated with disruption of transcriptional control of cellular genes. HTLV‐1 basic leucine‐zipper (bZIP) factor, HBZ, is encoded by the complementary strand of the provirus. We previously rep
## Abstract A total of 160 sera from HIV‐1 infected individuals from Tanzania were examined for their fine specificity characteristics relative to 9 synthetic peptides that define HIV‐1 gp160 epitopes. Immunorecessive and immunodominant epitopes were identified in both gp120 and gp41 based on serol