๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Humoral and cellular immune responses to dihydrolipoamide dehydrogenase (E3): lack of specificity for primary biliary cirrhosis

โœ Scribed by Hajime Tanaka; Takashi Maeda; Saburo Onishi; Yasutake Yamamoto


Book ID
114796937
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
686 KB
Volume
15
Category
Article
ISSN
0106-9543

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Autoantibody against dihydrolipoamide de
โœ Takashi Maeda; Bruce E. Loveland; Merrill J. Rowley; Dr. Ian R. Mackay ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 717 KB

Autoantibodies in primary biliary cirrhosis recognize mitochondrial 2-oxacid dehydrogenase complexes, particularly the E2 subunits. Reactivity with the E3 subunit, common to each of the enzyme complexes, was sought by immunoblotting, with sera screened at 1:100 instead of the conventional 1:1,000 di

Autoepitope mapping and reactivity of au
โœ Laurence Dubel; Atsushi Tanaka; Patrick S. Leung; Judy Van de Water; Ross Coppel ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 105 KB ๐Ÿ‘ 2 views

Primary biliary cirrhosis (PBC) is an autoimmune liver disease characterized by the presence of antimitochondrial antibodies (AMA) directed primarily against the E2 subunits of the pyruvate dehydrogenase complex, the branched chain 2-oxo-acid dehydrogenase complex, the 2-oxoglutarate dehydrogenase c

Characterization of the autoantibody res
โœ Jeremy M. Palmer; David E. Jones; Janet Quinn; Anna McHugh; Stephen J. Yeaman ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 171 KB ๐Ÿ‘ 2 views

Autoantibodies to the pyruvate dehydrogenase complex (PDC) are present in the serum of more than 95% of patients with primary biliary cirrhosis (PBC), the major epitope being the inner lipoyl domain of the E2 component. Immunoblotting suggests a similar prevalence of antibodies to a tightly associat