Human α-globin maps to pter-p13.3 in chromosome 16 distal to PGP

✍ Scribed by M. H. Breuning; K. Madan; M. Verjaal; J. T. Wijnen; P. Meera Khan; P. L. Pearson

• Book ID: 104703984
• Publisher: Springer
• Year: 1987
• Tongue: English
• Weight: 600 KB
• Volume: 76
• Category: Article
• ISSN: 0340-6717
• DOI: 10.1007/bf00283625

✦ Synopsis

Fibroblasts from a fetus with an unbalanced karyotype 46(XY), -16,+(16qter-16p13.3::4q31.1-4qter) were found to possess only one allele at the 3' hypervariable region (3'HVR) close to the alpha-globin locus and two alleles at the PGP locus. This places the alpha-globin locus at the very tip of 16p, distal to PGP.