## Abstract Human telomeric DNA consists of tandem repeats of the sequence 5′‐d(TTAGGG)‐3′. Guanine‐rich DNA, such as that seen at telomeres, forms G‐quadruplex secondary structures. Alternative forms of G‐quadruplex structures can have differential effects on activities involved in telomere mainte
✦ LIBER ✦
Human Telomeric Quadruplex Conformations Studied by Pulsed EPR
✍ Scribed by Vijay Singh; Mykhailo Azarkh; Thomas E. Exner; Jörg S. Hartig; Malte Drescher
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 399 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0044-8249
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Ras is a central constituent of the intracellular signal transduction that switches between its inactive state with GDP bound and its active state with GTP bound. A number of different X-ray structures are available. Different magnetic resonance techniques were used to characterise the conformationa