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Human telomerase is regulated by erythropoietin and transforming growth factor-β in human erythroid progenitor cells

✍ Scribed by Prade-Houdellier, N; Frébet, E; Demur, C; Gautier, E-F; Delhommeau, F; Bennaceur-Griscelli, A-L; Gaudin, C; Martinel, V; Laurent, G; Mansat-De Mas, V

Book ID
110058383
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
297 KB
Volume
21
Category
Article
ISSN
0887-6924

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Transforming growth factor-beta1 (TGF-beta1) has been described as an efficient growth inhibitor that maintains the CD34(+) hematopoietic progenitor cells in quiescence. The concept of high proliferative potential-quiescent cells or HPP-Q cells has been introduced as a working model to study the eff