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Human telomerase accelerates growth of lens epithelial cells through regulation of the genes mediating RB/E2F pathway

✍ Scribed by Xiang, Hua; Wang, Juan; Mao, Yingwei; Liu, Mingyao; Reddy, Venkat N; Li, David Wan-Cheng


Book ID
110066649
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
267 KB
Volume
21
Category
Article
ISSN
0950-9232

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## Abstract We investigated the effects of overexpression of the tuberous sclerosis‐1 and ‐2 (__TSC1/2__) gene products (hamartin and tuberin, respectively) in the human kidney epithelial cell line 293 with an inducible expression system. As we had observed previously in fibroblasts, 293 cells over