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Human T lymphocytes possess a limited in vitro life span

✍ Scribed by Nancy L. Perillo; Roy L. Walford; Margaret A. Newman; Rita B. Effros

Book ID
113371030
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
613 KB
Volume
24
Category
Article
ISSN
0531-5565

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## Abstract A number of normal human cell types have been shown to exhibit cellular senescence in vitro. We and others had found that fusion of normal human fibroblasts with immortal human cells yielded hybrids having limited lifespan. This indicated that the phenotype of cellular senescence is dom