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Human spleen cells mediating natural killing: Altered natural cytotoxicity of spleen effector cells from patients with carcinoma

✍ Scribed by Selman A. Ali; Catherine M. Hawrylowicz; Janet Peel; Clive Griffith; Robert C. Ress


Book ID
112295276
Publisher
Springer-Verlag
Year
1983
Tongue
English
Weight
783 KB
Volume
106
Category
Article
ISSN
1432-1335

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In patients with cancer, antibody-dependent cellular cytotoxicity (ADCC) may be used as a laboratory test or for enhancing immunotherapy with murine monoclonal or chimeric mouse/ human anti-tumor antibodies (mMAbs or cMAbs, respectively). We have established an ADCC assay with lgG, cMAb SF-25, using