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Human Spire Interacts with the Barbed End of the Actin Filament

✍ Scribed by Takuto Ito; Akihiro Narita; Tasuku Hirayama; Masayasu Taki; Shohei Iyoshi; Yukio Yamamoto; Yuichiro Maéda; Toshiro Oda


Book ID
116664527
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
990 KB
Volume
408
Category
Article
ISSN
0022-2836

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Profilin, a ubiquitous 12 to 15-kDa protein, serves many functions, including sequestering monomeric actin, accelerating nucleotide exchange on actin monomers, decreasing the critical concentration of the barbed end of actin filaments, and promoting actin polymerization when barbed ends are free. Mo