Human smooth muscle cells of the aorta and vena cava: Different sensitivity to the inhibition of proliferation by heparin in vitro

Bone morphogenetic protein-7 (osteogenic

Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro

✍ Haimanti Dorai; Slobodan Vukicevic; T. Kuber Sampath 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 352 KB 👁 2 views

Vascular proliferative disorders are characterized by migration and proliferation of vascular smooth muscle cells (SMCs), loss of expression of SMC phenotype, and enhanced extracellular matrix synthesis (e.g., type I collagen). We report here that bone morphogenetic protein-7 (BMP-7), a member of th