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Human single-chain antibodies specific to the tumor necrosis factor

✍ Scribed by M. A. Vikhrova; T. A. Batanova; L. R. Lebedev; L. N. Shingarova; L. A. Frank; M. P. Kirpichnikov; N. V. Tikunova

Book ID
111457203
Publisher
SP MAIK Nauka/Interperiodica
Year
2011
Tongue
English
Weight
798 KB
Volume
37
Category
Article
ISSN
1068-1620

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## Abstract Fusion constructs targeting tumor cells have significant potential applications against both solid tumors and hematologic malignancies. We developed a fusion construct of tumor necrosis factor (TNF) and a single‐chain antibody (scFvMEL) recognizing the gp240 antigen on human melanoma ce