Human Serum Albumin and the Enigma of Chronic Hepatitis Type B
✍ Scribed by Ulla Hellström; Staffan Sylvan
- Book ID
- 110860725
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 438 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0300-9475
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📜 SIMILAR VOLUMES
HBsAg is known to bind to human serum albumin polymerized by glutaraldehyde, human serum albumin has been found in preparations of HBsAg by several investigators. However, it is not yet known whether natural human serum albumin binds to hepatitis B virus under physiological conditions. We studied th
## Abstract HBsAg binds to a solid‐phase adsorbent consisting of polymerized human serum albumin (HSA) on glass particles. Both AD and AY antigenic subtypes of hepatitis B surface antigen (HBsAg) display this interaction. In either case, the binding to polymerized HSA is reduced in the presence of
hepatitis B virus DNA polymerase concentrations and may serve as indicators of viral replication.