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Human Safety and Pharmacokinetics of the CFC Alternative Propellants HFC 134a (1,1,1,2-Tetrafluoroethane) and HFC 227 (1,1,1,2,3,3,3-Heptafluoropropane) Following Whole-Body Exposure

✍ Scribed by H.H. Emmen; E.M.G. Hoogendijk; W.A.A. Klöpping-Ketelaars; H. Muijser; E. Duistermaat; J.C. Ravensberg; D.J. Alexander; D. Borkhataria; G.M. Rusch; B. Schmit


Book ID
115646984
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
362 KB
Volume
32
Category
Article
ISSN
0273-2300

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Liquid–air partition coefficients of 1,1
✍ Lena Ernstgård; Birger Lind; Melvin E. Andersen; Gunnar Johanson 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 156 KB

## Abstract Blood–air and tissue–blood coefficients (__λ__) are essential to characterize the uptake and disposition of volatile substances, e.g. by physiologically based pharmacokinetic (PBPK) modelling. Highly volatile chemicals, including many hydrofluorocarbons (HFC) have low solubility in liqu