Human Progesterone Receptor Gene Polymorphism PROGINS and Risk for Breast Cancer in Austrian Women
β Scribed by Gerhild Fabjani; Dan Tong; Klaus Czerwenka; Eva Schuster; Paul Speiser; Sepp Leodolter; Robert Zeillinger
- Book ID
- 110331173
- Publisher
- Springer US
- Year
- 2002
- Tongue
- English
- Weight
- 120 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0167-6806
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π SIMILAR VOLUMES
In a recent case-control study of epithelial ovarian cancer, Tong et al. 1 evaluated the possible association between cancer risk and the PROGINS allele of the progesterone receptor gene. This allele, a 306 bp Alu insertion in intron G of the gene, has been linked to ovarian cancer in several studie
## Abstract Estrogens, and to a lesser extent progesterones, influence the proliferation, differentiation and physiology of breast tissue as well as the development and progression of breast cancer. Genetic variants in the steroid hormone receptor genes __ESR1__ and __PGR__ (belonging to the nuclea