T-antigen of the human polyomavirus JC a
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Joanna Trojanek; Sidney Croul; Thu Ho; Jin Ying Wang; Armine Darbinyan; Michal N
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Article
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2005
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John Wiley and Sons
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English
⚖ 667 KB
## Abstract JC polyomavirus (JCV), which infects 90% of the human population, is detectable in human tumors. Its early protein, JCV T‐antigen, transforms cells in vitro and is tumorigenic in experimental animals. Although T‐antigen‐mediated transformation involves genetic alterations of the affecte